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cambridge-o-level-biology-5090-2026-2028:v1
productionAPI health
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Overview

4 Papers
71 Topics
52 Subtopics
300 Outcomes
2 Sources
840 Paper-topic rules

Status published Locked

Version label: v1 | Years: 2026–2028 | Content hash: sha256:8ed80f259a36d293a8723c2bb6fcdde2ee9042c865502681cb3b8c9ff2c2ea10 | Published: 2026-06-08T10:27:25+00:00 | Locked: 2026-06-08T10:27:25+00:00

p1 Paper 1 - Multiple Choice

Duration 60 min · Marks 40 · Weighting 30.00 · Structure fixed_items · Question count fixed 40 · Assembly exact_fixed_count

Allowed styles: multiple_choice / top_level → mcq

Patterns: 40

p2 Paper 2 - Theory

Duration 105 min · Marks 80 · Weighting 50.00 · Structure flexible_structured · Question count flexible_total_marks · Assembly exact_total_marks

Allowed styles: structured_response / top_level → structured_response short_answer / part → short_answer long_text / part → long_text fill_in_the_blanks / part → fill_in_the_blanks calculation_response / part → calculation_response data_response / part → data_response graph_interpretation / part → graph_interpretation table_completion_as_text / part → table_completion_as_text diagram_labeling / part → diagram_labeling canvas_drawing / part → canvas_drawing

Patterns: 3

p3 Paper 3 - Practical Test

Duration 90 min · Marks 40 · Weighting 20.00 · Structure flexible_practical · Question count flexible_total_marks · Assembly exact_total_marks

Allowed styles: structured_response / top_level → structured_response short_answer / part → short_answer long_text / part → long_text calculation_response / part → calculation_response data_response / part → data_response graph_interpretation / part → graph_interpretation table_completion_as_text / part → table_completion_as_text diagram_labeling / part → diagram_labeling canvas_drawing / part → canvas_drawing practical_planning / part → practical_planning practical_analysis_evaluation / part → practical_analysis_evaluation fill_in_the_blanks / part → fill_in_the_blanks

Patterns: 4

p4 Paper 4 - Alternative to Practical

Duration 60 min · Marks 40 · Weighting 20.00 · Structure flexible_alternative_practical · Question count flexible_total_marks · Assembly exact_total_marks

Allowed styles: structured_response / top_level → structured_response short_answer / part → short_answer long_text / part → long_text calculation_response / part → calculation_response data_response / part → data_response graph_interpretation / part → graph_interpretation table_completion_as_text / part → table_completion_as_text diagram_labeling / part → diagram_labeling canvas_drawing / part → canvas_drawing practical_planning / part → practical_planning practical_analysis_evaluation / part → practical_analysis_evaluation fill_in_the_blanks / part → fill_in_the_blanks

Patterns: 4

1 Cells

  • 1.1 Cell structure and function 6 outcomes
    • 1 Examine under the microscope, animal cells and plant cells from any suitable locally available material, using an appropriate temporary stai... p3, p4
    • 2 Draw diagrams to represent observations of the animal and plant cells examined above p2, p3, p4
    • 3 Identify on diagrams, photomicrographs or electron micrographs, the ribosomes, mitochondria, nucleus, cytoplasm and cell membrane in an anim... p2, p3, p4
    • 4 Identify on diagrams, photomicrographs or electron micrographs, the ribosomes, mitochondria, chloroplasts, nucleus, sap vacuole, cytoplasm,... p2, p3, p4
    • 5 Describe the structure of a bacterial cell, limited to: ribosomes, circular deoxyribonucleic acid (DNA) and plasmids, cytoplasm, cell membra... p1, p2
  • 1.2 Specialised cells, tissues and organs 3 outcomes
    • 1 Understand that cells can become specialised and that their structures are related to their specific functions, as illustrated by examples c... p1, p2
    • 2 Understand the terms cell, tissue, organ, organ system and organism as illustrated by examples covered in the syllabus p1, p2
    • 3 State and use the formula magnification = image size actual size p1, p2

2 Classification

  • 2.1 Concept and use of a classification system 4 outcomes
    • 1 Understand that organisms can be classified into groups by the features they share p1, p2
    • 2 Describe a species as a group of organisms that can reproduce to produce fertile offspring p1, p2
    • 3 Describe the binomial system of naming species as an internationally agreed system in which the scientific name of an organism is made up of... p1, p2
    • 4 Construct and use dichotomous keys based on identifiable features p2, p3, p4
  • 2.2 Features of organisms 6 outcomes
    • 1 State the main features used to place all organisms into one of the five kingdoms: Animal, Plant, Fungus, Prokaryote, Protoctist p1, p2
    • 2 State the main features used to place organisms into groups within the animal kingdom, limited to: (a) the main groups of vertebrates: mamma... p1, p2
    • 3 State the main features used to place organisms into groups within the plant kingdom, limited to ferns and flowering plants (dicotyledons an... p1, p2
    • 4 Classify organisms using the features identified in 2.2.1, 2.2.2 and 2.2.3 p1, p2
    • 5 State the main features of viruses, limited to protein coat and genetic material p1, p2

3 Movement into and out of cells

  • 3.1 Diffusion and osmosis 9 outcomes
    • 1 Describe the role of water as a solvent in organisms with reference to digestion, excretion and transport p1, p2
    • 2 Understand that the energy for diffusion and osmosis comes from the kinetic energy of random movement of molecules and ions p1, p2
    • 3 Understand diffusion as the net movement of molecules or ions from a region of their higher concentration to a region of their lower concent... p1, p2
    • 4 Investigate the factors that influence diffusion, limited to: surface area, temperature, concentration gradient and distance p3, p4
    • 5 Understand osmosis as the net movement of water molecules from a region of higher water potential to a region of lower water potential, thro... p1, p2
  • 3.2 Active transport 2 outcomes
    • 1 Understand active transport as the movement of molecules or ions into or out of a cell through the cell membrane, from a region of their low... p1, p2
    • 2 Explain the importance of active transport in ion uptake by root hair cells p1, p2

4 Biological molecules

  • 4.1 Biological molecules 3 outcomes
    • 1 List the chemical elements that make up: (a) carbohydrates (b) lipids (fats and oils) (c) proteins (d) DNA p1, p2
    • 2 State that large molecules are made from smaller molecules, limited to: starch, cellulose and glycogen from glucose; proteins from amino aci... p1, p2
    • 3 Describe and be able to do chemical tests for: (a) starch (iodine solution) (b) glucose and maltose (Benedict’s solution) (c) protein (biure... p1, p2

5 Enzymes

  • 5.1 Enzyme action 4 outcomes
    • 1 Describe a catalyst as a substance that increases the rate of a chemical reaction and is not changed by the reaction p1, p2
    • 2 Describe enzymes as proteins that function as biological catalysts and are involved in all metabolic reactions p1, p2
    • 3 Explain enzyme action with reference to the substrate, active site, enzyme-substrate complex, and product p1, p2
    • 4 Explain the specificity of enzymes in terms of the complementary shape and fit of the active site with the substrate (‘lock and key’ hypothe... p1, p2
  • 5.2 Effects of temperature and pH 3 outcomes
    • 1 Understand that the progress of enzyme-catalysed reactions can be followed by measuring the concentrations of reactants and products p1, p2
    • 2 Investigate and describe the effects of temperature and pH on enzyme activity p3, p4
    • 3 Explain the effect of changes in temperature and pH on enzyme activity in terms of kinetic energy, shape and fit, denaturation and the frequ... p1, p2

6 Plant nutrition

  • 6.1 Photosynthesis 9 outcomes
    • 1 Understand that photosynthesis is the process by which plants make carbohydrates from raw materials using energy from light p1, p2
    • 2 State that chlorophyll is a green pigment that is found in chloroplasts p1, p2
    • 3 State that chlorophyll transfers light energy into chemical energy for the formation of glucose and other carbohydrates p1, p2
    • 4 Outline the subsequent use and storage of the carbohydrates made in photosynthesis, limited to: (a) starch as an energy store (b) cellulose... p1, p2
    • 5 State the word equation and balanced chemical equation for photosynthesis p1, p2
  • 6.2 Leaf structure 2 outcomes
    • 1 State that most leaves have a large surface area and are thin, and explain how these features are adaptations for photosynthesis p1, p2
    • 2 Identify and label the cuticle, cellular and tissue structures of a dicotyledonous leaf, as seen in diagrams or photomicrographs, and explai... p2, p3, p4
  • 6.3 Mineral nutrition 2 outcomes
    • 1 Explain the importance of nitrate ions for making amino acids, required for the production of proteins p1, p2
    • 2 Explain the importance of magnesium ions for making chlorophyll p1, p2

7 Transport in flowering plants

  • 7.1 Uptake and transport of water and ions 3 outcomes
    • 1 Relate the structure of root hair cells to their function of water and ion uptake p1, p2
    • 2 Outline the pathway taken by water through the root, stem and leaf, limited to: root hair cells, root cortex cells, xylem and mesophyll cell... p1, p2
    • 3 Investigate, using a suitable stain, the pathway of water in a cut stem p3, p4
  • 7.2 Transpiration and translocation 9 outcomes
    • 1 Describe transpiration as the loss of water vapour from leaves p1, p2
    • 2 Understand that water evaporates from the surfaces of the mesophyll cells into air spaces and then diffuses out of the leaves through the st... p1, p2
    • 3 Explain: (a) the effects of wind speed, and the variation of temperature, humidity and light intensity on transpiration rate (b) how wiltin... p1, p2
    • 4 Investigate the effects of wind speed, light intensity and temperature variation on transpiration rate p3, p4
    • 5 Explain the mechanism by which water moves upwards in the xylem in terms of a transpiration pull that draws up a column of water molecules,... p1, p2

8 Human nutrition

  • 8.1 Diet 3 outcomes
    • 1 List the principal sources of, and describe the dietary importance of, carbohydrates, lipids, proteins, vitamins (C and D only), mineral sal... p1, p2
    • 2 Name the diseases and describe the symptoms resulting from deficiencies of vitamin C (scurvy), vitamin D (rickets), calcium (rickets) and ir... p1, p2
    • 3 Understand the concept of a balanced diet p1, p2
  • 8.2 Human digestive system 14 outcomes
    • 1 Identify the main regions of the digestive system: mouth, salivary glands, oesophagus, stomach, small intestine (duodenum and ileum), pancre... p1, p2
    • 2 Explain why most foods must be digested before they can be absorbed p1, p2
    • 3 Describe physical digestion as the breakdown of food into smaller pieces without chemical change to the food molecules p1, p2
    • 4 Describe chemical digestion as the breakdown of large molecules into small molecules p1, p2
    • 5 State that physical digestion increases the surface area of food for the action of enzymes in chemical digestion p1, p2
  • 8.3 Absorption and assimilation 7 outcomes
    • 1 State that the small intestine is the region where nutrients are absorbed p1, p2
    • 2 Understand that absorption (by diffusion, osmosis and active transport) is the movement of nutrients from the intestines into cells lining t... p1, p2
    • 3 Understand that assimilation is the uptake and use by cells of nutrients from the blood p1, p2
    • 4 Describe the structure of a villus and the roles of capillaries and lacteals p1, p2
    • 5 Explain the significance of villi and microvilli in increasing the internal surface area of the ileum p1, p2

9 Human gas exchange

  • 9.1 Human gas exchange 9 outcomes
    • 1 Describe the features of gas exchange surfaces in humans, limited to: large surface area, thin surface, good blood and air supply p1, p2
    • 2 State the percentages of the gases in atmospheric air p1, p2
    • 3 Investigate and explain the differences between inspired and expired air p3, p4
    • 4 Identify, on diagrams and images, the larynx, trachea, lungs, bronchi, bronchioles, alveoli and associated capillaries p2, p3, p4
    • 5 State the characteristics of, and describe the role of, the exchange surface of the alveoli in gas exchange p1, p2

10 Respiration

  • 10.1 Respiration 3 outcomes
    • 1 Describe respiration as the chemical reactions in all living cells that release energy from glucose p1, p2
    • 2 State the uses of energy in living organisms including muscle contraction, protein synthesis, cell division, active transport, growth, the p... p1, p2
    • 3 Investigate and describe the effect of temperature on respiration in yeast p3, p4
  • 10.2 Aerobic respiration 2 outcomes
    • 1 Describe aerobic respiration as the release of a relatively large amount of energy by the breakdown of glucose in the presence of oxygen p1, p2
    • 2 State the word equation and balanced chemical equation for aerobic respiration p1, p2
  • 10.3 Anaerobic respiration 5 outcomes
    • 1 Describe anaerobic respiration as the release of a relatively small amount of energy by the breakdown of glucose without using oxygen p1, p2
    • 2 State the word equation for anaerobic respiration in humans p1, p2
    • 3 State the word equation for anaerobic respiration in yeast p1, p2
    • 4 Explain why lactic acid builds up in muscles and blood during vigorous exercise causing Excess Post-exercise Oxygen Consumption (EPOC) or an... p1, p2
    • 5 Outline how the oxygen debt is removed after exercise, limited to: (a) continuation of fast heart rate to transport lactic acid in blood fro... p1, p2

11 Transport in humans

  • 11.1 Circulatory system 3 outcomes
    • 1 Describe the circulatory system as a system of blood vessels with a pump and valves to ensure one- way flow of blood p1, p2
    • 2 Describe a double circulation as a system in which blood passes through the heart twice for each complete circuit p1, p2
    • 3 Understand that a double circulation provides a low pressure circulation to the lungs and a high pressure circulation to the body tissues p1, p2
  • 11.2 Heart 8 outcomes
    • 1 Identify the structures of the mammalian heart, limited to: the muscular wall, the septum, the left and right ventricles and atria, atrioven... p1, p2
    • 2 Explain the relative thickness: (a) of the muscle walls of the left and right ventricles (b) of the muscle walls of the atria compared to th... p1, p2
    • 3 Describe the functioning of the heart in terms of the contraction of muscles of the atria and ventricles and the action of the valves in a h... p1, p2
    • 4 State that blood is pumped away from the heart in arteries and returns to the heart in veins p1, p2
    • 5 State that the activity of the heart may be monitored by electrocardiogram (ECG), pulse rate and listening to sounds of valves closing p1, p2
  • 11.3 Blood vessels 3 outcomes
    • 1 Name the main blood vessels that carry blood to and from the heart, lungs, liver and kidneys, limited to: aorta, vena cava, pulmonary artery... p1, p2
    • 2 Describe, and identify on diagrams and photomicrographs, the structure of arteries, veins and capillaries, limited to: (a) relative thicknes... p2, p3, p4
    • 3 Explain how the structure of arteries, veins and capillaries is related to the pressure of the blood that they transport p1, p2
  • 11.4 Blood 4 outcomes
    • 1 Identify red and white blood cells (lymphocytes and phagocytes) as seen under the light microscope on prepared slides, and in diagrams and p... p2, p3, p4
    • 2 List the components of blood as red blood cells, white blood cells, platelets and plasma p1, p2
    • 3 State the functions of the components of blood: (a) red blood cells – oxygen transport (b) white blood cells – antibody production by lympho... p1, p2
    • 4 Describe the transfer of substances between blood in capillaries, tissue fluid and body cells p1, p2

12 Disease and immunity

  • 12.1 Disease 16 outcomes
    • 1 Describe a pathogen as a disease-causing organism p1, p2
    • 2 Describe a transmissible disease as a disease in which the pathogen can be passed from one host to another p1, p2
    • 3 Understand that a pathogen may be transmitted: (a) through direct contact, including through blood or other body fluids (b) indirectly, incl... p1, p2
    • 4 Describe the human body’s barriers to the entry of pathogens, limited to: skin, hairs in the nose, mucus, stomach acid p1, p2
    • 5 Understand the role of the mosquito as a vector of disease p1, p2
  • 12.2 Antibiotics 4 outcomes
    • 1 Describe a drug as any substance taken into the body that modifies or affects chemical reactions in the body p1, p2
    • 2 Describe the use of antibiotics for the treatment of bacterial infection p1, p2
    • 3 State that antibiotics kill bacteria but do not affect viruses p1, p2
    • 4 Explain how development of antibiotic-resistant bacteria, including MRSA, can be minimised by using antibiotics only when essential p1, p2
  • 12.3 Immunity 11 outcomes
    • 1 Describe active immunity as defence against a pathogen by antibody production in the body p1, p2
    • 2 State that each pathogen has its own antigens, which have specific shapes p1, p2
    • 3 Describe antibodies as proteins that bind to antigens leading to direct destruction of pathogens, or marking of pathogens for destruction by... p1, p2
    • 4 State that specific antibodies have complementary shapes which fit specific antigens p1, p2
    • 5 Explain that active immunity is gained after an infection by a pathogen, or by vaccination p1, p2

13 Excretion

  • 13.1 Excretion 3 outcomes
    • 1 Describe excretion as the removal of toxic materials and the waste products of metabolism from organisms p1, p2
    • 2 State that carbon dioxide is a waste product of respiration, which is excreted through the lungs p1, p2
    • 3 State that urea is a toxic waste product produced in the liver from the breakdown of excess amino acids p1, p2
  • 13.2 Urinary system 6 outcomes
    • 1 Identify, on diagrams, the kidneys, ureters, bladder and urethra and state the function of each (the function of the kidney should be descri... p2, p3, p4
    • 2 Explain the need for excretion, limited to toxicity of urea p1, p2
    • 3 Outline the structure of a nephron and its associated blood vessels, limited to: Bowman’s capsule, glomerulus, tubules, loop of Henle and co... p1, p2
    • 4 Outline the function of a nephron and its associated blood vessels, limited to: (a) the role of the glomerulus in the filtration from the bl... p1, p2
    • 5 Describe the role of the liver in the assimilation of amino acids by converting them to proteins p1, p2

14 Coordination and control

  • 14.1 Mammalian nervous system 10 outcomes
    • 1 State that the nervous system (brain, spinal cord and nerves) coordinates and regulates body functions p1, p2
    • 2 Describe the mammalian nervous system in terms of: (a) the central nervous system (CNS) consisting of the brain and the spinal cord (b) the... p1, p2
    • 3 Identify, on diagrams, sensory, relay and motor neurones p2, p3, p4
    • 4 State that electrical impulses travel along neurones p1, p2
    • 5 Describe simple reflex arcs in terms of receptor, sensory neurone, relay neurone, motor neurone and effector (muscles and glands) p1, p2
  • 14.2 Mammalian sense organs 5 outcomes
    • 1 Describe sense organs as groups of receptor cells responding to specific stimuli: light, sound, touch, temperature and chemicals p1, p2
    • 2 Identify, on a diagram, the structures of the eye, limited to: cornea, iris, pupil, lens, ciliary muscles, suspensory ligaments, retina, fov... p2, p3, p4
    • 3 Describe the function of each part of the eye, limited to: (a) cornea – refracts light (b) iris – controls how much light enters the pupil (... p1, p2
    • 4 Explain the pupil reflex in terms of light intensity and antagonistic action of circular and radial muscles in the iris p1, p2
    • 5 Explain accommodation to view near and distant objects in terms of the contraction and relaxation of the ciliary muscles, tension in the sus... p1, p2
  • 14.3 Mammalian hormones 4 outcomes
    • 1 Describe a hormone as a chemical substance, produced by a gland and carried by the blood, which alters the activity of one or more specific... p1, p2
    • 2 Identify, on a diagram, endocrine glands that produce hormones and state the hormones they produce, limited to: (a) the adrenal glands – pro... p2, p3, p4
    • 3 Understand the role of the hormone adrenaline, produced by the adrenal glands, in increasing the blood glucose concentration and heart rate... p1, p2
    • 4 Compare nervous and hormonal control, limited to speed of action and duration of effect p1, p2
  • 14.4 Homeostasis 2 outcomes
    • 1 Describe homeostasis as the maintenance of a constant internal environment p1, p2
    • 2 Explain the concept of control by negative feedback with reference to a set point p1, p2
  • 14.5 Temperature control 4 outcomes
    • 1 Identify, on a diagram of the skin: hairs, hair erector muscles, sweat glands, receptors, sensory neurones, blood vessels and fatty tissue p2, p3, p4
    • 2 Describe the role of insulation in maintaining a constant internal body temperature in mammals p1, p2
    • 3 Describe the roles of the hypothalamus and of temperature receptors in the skin in maintaining a constant internal body temperature in mamma... p1, p2
    • 4 Explain how each of the following processes contributes to the maintenance of constant internal body temperature in mammals: (a) sweating (b... p1, p2
  • 14.6 Blood glucose control 3 outcomes
    • 1 Explain the need to control blood glucose concentration p1, p2
    • 2 Describe the control of blood glucose concentration by the liver and pancreas and the roles of insulin and glucagon p1, p2
    • 3 Describe the signs of Type 1 diabetes (limited to increased blood glucose concentration and glucose in urine) and its treatment (administrat... p1, p2

15 Coordination and response in plants

  • 15.1 Coordination and response in plants 4 outcomes
    • 1 Describe gravitropism as a response in which parts of a plant grow towards or away from gravity p1, p2
    • 2 Describe phototropism as a response in which parts of a plant grow towards or away from light p1, p2
    • 3 Explain the role of auxin in controlling shoot growth, limited to: (a) auxin is made in the shoot tip (b) auxin spreads through the plant fr... p1, p2
    • 4 Investigate gravitropism and phototropism in shoots and roots p3, p4

16 Development of organisms and continuity of life

  • 16.1 Nuclear division 10 outcomes
    • 1 Understand that chromosomes contain DNA, which carries genetic information in the form of genes p1, p2
    • 2 Describe a haploid nucleus as a nucleus containing a single set of chromosomes p1, p2
    • 3 Describe a diploid nucleus as a nucleus containing two sets of chromosomes p1, p2
    • 4 State that in a diploid cell there is a pair of each type of chromosome and in a human diploid cell there are 23 pairs p1, p2
    • 5 Describe mitosis as nuclear division giving rise to genetically identical cells in which the chromosome number is maintained (details of sta... p1, p2
  • 16.2 Asexual and sexual reproduction 4 outcomes
    • 1 Describe asexual reproduction as a process resulting in the production of genetically identical offspring from one parent p1, p2
    • 2 Identify examples of asexual reproduction p1, p2
    • 3 Describe sexual reproduction as the process involving the fusion of haploid nuclei (fertilisation) to form a diploid zygote and the producti... p1, p2
    • 4 Discuss the advantages and disadvantages of asexual reproduction and sexual reproduction p1, p2
  • 16.3 Sexual reproduction in plants 13 outcomes
    • 1 Identify and draw the sepals, petals, stamens (anthers and filaments) and carpels (stigmas, styles, ovaries and ovules) of an insect-pollina... p1, p2
    • 2 Identify and draw the anthers and stigmas of a wind-pollinated flower p1, p2
    • 3 Relate the structure of the parts of flowers to their functions, limited to the parts listed in 16.3.1 p1, p2
    • 4 Compare the flower structure and the pollen from insect-pollinated and wind-pollinated flowers p1, p2
    • 5 Outline the process of pollination and distinguish between self-pollination and cross-pollination p1, p2
  • 16.4 Sexual reproduction in humans 13 outcomes
    • 1 Identify, on diagrams of the male reproductive system: the testes, scrotum, sperm ducts, prostate gland, urethra and penis, and describe the... p2, p3, p4
    • 2 Identify, on diagrams of the female reproductive system: the ovaries, oviducts, uterus, cervix and vagina, and describe their functions p2, p3, p4
    • 3 Explain how the structure of a sperm cell is related to its function, limited to: flagellum, mitochondria and enzymes in the acrosome p1, p2
    • 4 Explain how the structure of an egg cell is related to its function, limited to energy stores and the jelly coat that changes at fertilisati... p1, p2
    • 5 Describe fertilisation as the fusion of the nuclei from a male gamete (sperm) and a female gamete (egg cell) p1, p2

17 Inheritance

  • 17.1 Variation 5 outcomes
    • 1 Describe variation as differences between individuals of the same species p1, p2
    • 2 Understand that continuous variation results in a range of phenotypes between two extremes, including body length and body mass p1, p2
    • 3 Understand that discontinuous variation results in a limited number of phenotypes with no intermediates, including ABO blood groups, seed sh... p1, p2
    • 4 Understand that discontinuous variation is usually caused by genes only and continuous variation is caused by genes and the environment p1, p2
    • 5 Investigate and describe examples of continuous and discontinuous variation p3, p4
  • 17.2 DNA 5 outcomes
    • 1 Describe the structure of a DNA molecule: (a) two strands coiled together to form a double helix (b) each strand is made up of a chain of nu... p1, p2
    • 2 Define a gene as a length of DNA that codes for a protein p1, p2
    • 3 Explain that DNA controls cell function by controlling the production of proteins, including enzymes p1, p2
    • 4 State that the sequence of bases in a gene determines the sequence of amino acids needed to make a specific protein (knowledge of the detail... p1, p2
    • 5 Understand that different sequences of amino acids give different shapes to protein molecules p1, p2
  • 17.3 Inheritance 12 outcomes
    • 1 Describe inheritance as the transmission of genetic information from generation to generation p1, p2
    • 2 Define an allele as an alternative form of a gene p1, p2
    • 3 Understand and use the terms: dominant, recessive, phenotype, genotype, homozygous and heterozygous p1, p2
    • 4 Use genetic diagrams, including Punnett squares, to predict the results of monohybrid crosses and calculate phenotypic ratios, limited to 1... p2, p3, p4
    • 5 Explain why observed ratios often differ from expected ratios, especially when there are small numbers of offspring p1, p2
  • 17.4 Selection 5 outcomes
    • 1 Describe natural selection with reference to: (a) variation within populations (b) production of many offspring (c) struggle for survival, i... p1, p2
    • 2 Describe how the inherited features of a population can evolve over time as a result of natural selection p1, p2
    • 3 Describe the development of strains of antibiotic-resistant bacteria, including MRSA, as an example of natural selection p1, p2
    • 4 Describe artificial selection (selective breeding) with reference to: (a) selection by humans of animals or plants with desirable features (... p1, p2
    • 5 Describe the role of artificial selection in the production of economically important plants and animals p1, p2

18 Biotechnology and genetic modification

  • 18.1 Biotechnology 5 outcomes
    • 1 Explain the role of yeast in the production of bread and ethanol p1, p2
    • 2 Understand that bacteria are useful in biotechnology and genetic modification due to their rapid reproduction rate and their ability to make... p1, p2
    • 3 Discuss why bacteria are useful in biotechnology and genetic modification, limited to: (a) no ethical concerns over their manipulation and g... p1, p2
    • 4 Describe how fermenters can be used for the large-scale production of useful products by bacteria and fungi, including the conditions that n... p1, p2
    • 5 Describe the use of: (a) enzymes in biological washing powders (b) pectinase for fruit juice production (c) lactase for lactose-free milk p1, p2
  • 18.2 Genetic modification 4 outcomes
    • 1 Describe genetic modification as changing the genetic material of an organism by removing, changing or inserting individual genes p1, p2
    • 2 Understand that the gene that controls the production of human insulin has been inserted into bacterial DNA, for commercial production of in... p1, p2
    • 3 Outline the use of genetic modification in crop plants by inserting genes: (a) to confer resistance to herbicides (b) to confer resistance t... p1, p2
    • 4 Discuss potential advantages and risks of genetic modification, limited to modifying crop plants and bacteria p1, p2

19 Relationships of organisms with one another and with the environment

  • 19.1 Energy flow 10 outcomes
    • 1 Understand that the Sun is the principal source of energy input to most biological systems p1, p2
    • 2 Explain why most forms of life are completely dependent on photosynthesis p1, p2
    • 3 Describe the flow of energy through food chains and webs including energy from light and energy in living organisms and its eventual transfe... p1, p2
    • 4 Construct and interpret simple food chains p2, p3, p4
    • 5 Understand the terms producer, consumer, herbivore, carnivore and decomposer p1, p2
  • 19.2 Nutrient cycles 3 outcomes
    • 1 Describe the carbon cycle, limited to: photosynthesis, respiration, feeding, decomposition, formation of fossil fuels and combustion p1, p2
    • 2 Outline the nitrogen cycle in making nitrogen available for plant and animal protein, limited to: (a) decomposition of plant and animal prot... p1, p2
    • 3 Outline the role of fungi and bacteria in decomposition p1, p2
  • 19.3 Ecosystems and biodiversity 6 outcomes
    • 1 Describe a population as a group of organisms of one species, living in the same area, at the same time p1, p2
    • 2 Describe a community as all of the populations of different species in an ecosystem p1, p2
    • 3 Describe an ecosystem as a unit containing the community of organisms and their environment, interacting together p1, p2
    • 4 Describe biodiversity as the number of different species that live in an area p1, p2
    • 5 Identify and state the factors affecting the rate of population growth for a population of an organism, limited to: food supply, competition... p1, p2
  • 19.4 Effects of humans on ecosystems 3 outcomes
    • 1 Outline the causes and describe the consequences of deforestation, limited to its effects on: biodiversity, extinction, loss of soil, floodi... p1, p2
    • 2 Describe the impacts humans have through: (a) over-harvesting of plant and animal species (b) introducing a non-native species to an ecosyst... p1, p2
    • 3 Describe the harmful effects of: (a) water pollution by untreated sewage and nitrogen-containing fertilisers leading to eutrophication, lim... p1, p2
  • 19.5 Conservation 4 outcomes
    • 1 Discuss reasons for conservation of species with reference to: (a) maintenance of biodiversity (b) reducing extinction (c) protecting vulner... p1, p2
    • 2 Explain how forests can be conserved using education, protected areas, quotas and replanting p1, p2
    • 3 Explain how fish stocks can be conserved using education, closed seasons, protected areas, controlled net types and mesh size, quotas and mo... p1, p2
    • 4 Describe a sustainable resource as one which is produced as rapidly as it is removed from the environment so that it does not run out p1, p2
Type Title URL Confidence Actions
official_subject_page Cambridge O Level Biology 5090 subject page https://www.cambridgeinternational.org/programmes-... official_subject_page
official_syllabus Official source Cambridge O Level Biology 5090 syllabus for examination in 2026, 2027 and 2028 https://www.cambridgeinternational.org/Images/6973... official_component_structure

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